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AUA2021 State-of-the-Art Lecture: Penile Fractures: Unique Etiologies and Scenarios
By: Kristina Buscaino, DO; Raul Fernandez-Crespo, MD; Justin Parker, MD; Rafael Carrion, MD | Posted on: 06 Aug 2021
Introduction
A fractured penis is typically the result of a forceful bending trauma to an erect penis; not all trauma results in this rare urological emergency.1,2 A tear in the tunica albuginea, in which the patient typically hears a “snapping” sound followed by sharp penile pain and prompt detumescence, characterizes this (fig. 1).2-4 A hematoma-ecchymosis then develops, generating its characteristic eggplant deformity, and the penis typically pointing to the contralateral side of the injury (fig. 2).1 Despite its diagnosis being customarily performed and confirmed on clinical findings and surgical exploration, respectively, penile ultrasound and magnetic resonance imaging (MRI) are useful especially in equivocal cases (fig. 3).2,5,6
In Western culture, penile fractures (PFs) are routinely associated with missed intromission during sexual intercourse, while in other parts of the world such as the Middle East, penile manipulation, known as “Taghaandan,” is the most common culprit.6,7 Unique scenarios can be encountered, such as post-intralesional injections of collagenase Clostridium histolyticum (CCH) and recurrent fractures, in which the algorithmic treatment may differ.
Recurrent PF
The occurrence of a recurrent PF is an even rarer event. In the literature it has been reported to occur in the same area of a previous fracture, in a different location in the ipsilateral corpora and even in the contralateral corpora.8-14 After a PF has been repaired, the deposition of collagen is usually completed after 6 weeks; after this, collagen remodeling will occur and the final tensile strength of the tissue will continue to transpire for up to 2 years.9 Fractures that occur at the same site suggest that unwounded tissue will still have more strength than scarred tissue.8,9 However, other authors have suggested that this fibrotic scar tissue can predispose to fractures at a different location in the ipsilateral corpora.12,15 The reasoning for this is that the surrounding uninjured corpora could be considered weaker when compared to the inelastic scar overlying a previously healed fracture.12 This inelastic scar tissue could also act as a source of unmatched axial pressure distribution within the corpora, leading to a fracture in the contralateral side.8,13
Surgical repair for recurrent fractures is recommended. The use of a bovine pericardium patch to reinforce the sutured site has been reported with successful outcome.8
PF Post-Intralesional CCH Injection
PFs occurring after CCH injections usually occur at the site of injection.16 Although sexual trauma is the main cause of these fractures, they have also been reported with penile modeling, nighttime tumescence, and even with the use of a vacuum erection device.16-18 These occur due to the ongoing degradation of tunica; therefore complete abstinence without any type of sexual activity is recommended for 4 weeks after starting each cycle due to the continuous effects of CCH on the tunica.17,19 Therefore, any correction or surgical repair to the area of injury may be violated until penile tissue remodeling is completed.17
Conservative management should be considered in PF occurring post-intralesional CCH injection, especially in patients who are hemodynamically stable, without worsening hematoma or a urethral injury.16,17 Compressive dressing, oral analgesics and penoscrotal elevation should be utilized in this specific scenario.17 When these fractures have been surgically repaired, poor tissue quality has been noted which could make appropriate tunical closure difficult, even requiring the use of a graft.19 It is important to note that no significant differences regarding erectile function, changes in penile curvature, and physician and patient satisfaction were noted among the group that underwent surgical exploration/repair and conservative management.19
Conclusion
Despite surgical management being the recommended management for PF, the final decision for care should be determined by the etiology and the circumstances in which the fracture occurred. In cases of recurrent fractures, immediate repair should be performed and a graft can be considered when the fracture occurs at the same site to further improve the strength in this area. In PF post-CCH therapy, conservative management should be considered. However, if there is concomitant urethral injury or expanding hematoma, surgical repair should be performed. If surgical intervention is to be performed, one can also consider a graft for repair, since the area at the injected site will continuously remodel and have weaker tensile strength.
- Godec CJ, Reiser R and Logush AZ: The erect penis–injury prone organ. J Trauma 1988; 28: 124.
- Morey AF, Brandes S, Dugi DD 3rd et al: Urotrauma: AUA Guideline. J Urol 2014; 192: 327.
- Dias-Filho AC, Fregonesi A, Martinez CAT et al: Can the snapping sound discriminate true from false penile fractures? Bayesian analysis of a case series of consecutively treated penile fracture patients. Int J Impot Res 2020; 32: 446.
- Izzo L, Izzo S, Pugliese F et al: The role of imaging in penile fracture. Our experience. Ann Ital Chir 2019; 90: 330.
- Morey AF, Broghammer JA, Hollowell CMP et al: Urotrauma guideline 2020: AUA Guideline. J Urol 2021; 205: 30.
- Szabo D, Shah N and Baradaran N: Evaluation and management of penile fracture. AUA Update Series 2020; 39: lesson 21.
- Falcone M, Garaffa G, Castiglione F et al: Current management of penile fracture: an up-to-date systematic review. Sex Med Rev 2018; 6: 253.
- Nascimento B, Guglielmetti GB, Miranda EP et al: Recurrent penile fracture–case report and alternative surgical approach. Sex Med 2018; 6: 263.
- Kattan S, Youssef A, Onuora V et al: Recurrent ipsilateral fracture of the penis. Injury 1993; 24: 685.
- Punekar SV and Kinne JS: Penile refracture. BJU Int 1999; 84: 183.
- Naraynsingh V, Maharaj R, Dan D et al: Second fracture of the ipsilateral corpus cavernosum. Injury Extra 2011; 42: 43.
- Ridyard DG, Phillips EA and Munarriz R: Recurrent penile fracture: a case report and review of literature. J Integr Nephrol Androl 2015; 2: 132.
- Sharma S, Suryavanshi M, Sharma S et al: Contralateral fracture of the penis with concomitant urethral injury–report of a rare case. Afr J Urol 2009; 15: 103.
- Du J, Mason DF and Broome KE: Penile fracture: second episode in 5 years. ANZ J Surg 2012; 82: 856.
- Barros R, Guimarães M, Nascimento C Jr et al: Penile refracture: a preliminary report. Int Braz J Urol 2018; 44: 800.
- Hughes WM, Natale C and Hellstrom WJG: The management of penile fracture: a review of the literature with special consideration for patients undergoing collagenase Clostridium histolyticum injection therapy. Curr Urol Rep 2021; 22: 13.
- Beilan JA, Wallen JJ, Baumgarten AS et al: Intralesional injection of collagenase Clostridium histolyticum may increase the risk of late-onset penile fracture. Sex Med Rev 2018; 6: 272.
- Beilan JA, Baumgarten AS, Bickell M et al: Suspected penile fracture after Xiaflex injection and use of a VED. Urology 2016; 98: 4.
- Yafi FA, Anaissie J, Zurawin J et al: Results of SMSNA survey regarding complications following intralesional injection therapy with collagenase Clostridium histolyticum for Peyronie’s disease. J Sex Med 2016; 13: 684.